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The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1) | Journal of Perinatology
To assess the impact of milrinone administration on time spent on nitric oxide (iNO) in infants with acute pulmonary hypertension (aPH). We hypothesized that intravenous milrinone used in conjunction with iNO would reduce the time on iNO therapy and the time spent on invasive ventilation in infants ?34 weeks gestation with a diagnosis of aPH. We aimed to assess the practicality of instituting the protocol and contributing to a sample size calculation for a definitive multicentre study. This was a multicentre, randomized, double-blind, two arm pilot study, with a balanced (1:1) allocation. Infants with a gestation ?34 weeks and a birth weight ?2000 grams aPH, an oxygenation index of ?10, and commenced on iNO were eligible. Participants on iNO were assigned to either a milrinone infusion (intervention) or a normal saline infusion (placebo) for up to 35?h. The primary outcome was time on iNO and feasibility of conducting the protocol. The trial was terminated early after 4 years of enrollment due to poor recruitment. Four infants were allocated to the intervention arm and 5 to the placebo arm. The groups were well matched for baseline variables. No differences were seen in any of the primary or secondary outcomes. Conducting an interventional trial in the setting of acute pulmonary hypertension in infants is not feasible using our current approach. Future studies in this area require alternative trial design to improve recruitment as this topic remains understudied in the neonatal field. www.isrctn.com ; ISRCTN:12949496; EudraCT Number:2014-002988-16
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With the introduction of girls wrestling to the IGHSAU for the 2022-23 season, the Jayettes are excited to see what they’re capable of as the sport continues to evolve in Iowa.
Oklahoma Football: 10 best quotes from Brent Venables Tuesday presser
10 of the best quotes from Brent Venables’ Tuesday press conference.
University of Sioux Falls Head Football Coach Jon Anderson Steppi
As the 2022 season comes to a close, the University of Sioux Falls and Head Football Coach Jon Anderson are parting ways.
The Des Moines Register
Iowa’s independent voters still drive elections | The Gazette
Neither political party thinks Tuesday’s election results make Iowa a “red state.”
Appeals court ruling keeps Biden student debt plan on hold - Los Angeles Times
Biden’s plan to forgive student loan debt for millions of borrowers lost another battle in court Monday when a panel agreed to a preliminary injunction.
AP Top 25: No. 1 South Carolina, No. 2 Stanford showdown set National News - Bally Sports
South Carolina remains the unanimous choice at No. 1 in The Associated Press women's basketball poll
3 things that stood out in Wisconsin football's loss at Iowa
The Badgers held Iowa to 146 yards and 2.1 yards per play. Here's what we learned from an otherwise sloppy showing.
Lubbock Avalanche-Journal
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Power Outage FAQs
What is Power Outage?
Power outage (also called a power cut, a power blackout, power failure or a blackout) is a short-term or a long-term loss of the electric power to a particular area.
What Causes Power Outages?
- Severe weather (high winds, lightning, winter storms, heat waves, rain or flooding can cause damage to power lines or equipment);
- Other damage to electric transmission lines (vehicle accidents, trees, and animals can cause damage to power lines or equipment);
- Repairing, maintenance or upgrades on power lines and equipment.
What are the Top Outage Safety Tips?
- Stay away from the downed power lines, park vehicles in protected areas;
- Unplug appliances and electronics, limit cell phone use to conserve battery life;
- Use portable generators outdoors only, well away from open windows and doors;
- Pack perishable foods into a cooler, keep refrigerator and freezer doors shut as much as possible.
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Peterson, Iowa
| City | Peterson |
| County | Clay |
| State | Iowa (IA) |
| Country | United States |
| Zip Codes | 51047 |