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The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1) | Journal of Perinatology
To assess the impact of milrinone administration on time spent on nitric oxide (iNO) in infants with acute pulmonary hypertension (aPH). We hypothesized that intravenous milrinone used in conjunction with iNO would reduce the time on iNO therapy and the time spent on invasive ventilation in infants ?34 weeks gestation with a diagnosis of aPH. We aimed to assess the practicality of instituting the protocol and contributing to a sample size calculation for a definitive multicentre study. This was a multicentre, randomized, double-blind, two arm pilot study, with a balanced (1:1) allocation. Infants with a gestation ?34 weeks and a birth weight ?2000 grams aPH, an oxygenation index of ?10, and commenced on iNO were eligible. Participants on iNO were assigned to either a milrinone infusion (intervention) or a normal saline infusion (placebo) for up to 35?h. The primary outcome was time on iNO and feasibility of conducting the protocol. The trial was terminated early after 4 years of enrollment due to poor recruitment. Four infants were allocated to the intervention arm and 5 to the placebo arm. The groups were well matched for baseline variables. No differences were seen in any of the primary or secondary outcomes. Conducting an interventional trial in the setting of acute pulmonary hypertension in infants is not feasible using our current approach. Future studies in this area require alternative trial design to improve recruitment as this topic remains understudied in the neonatal field. www.isrctn.com ; ISRCTN:12949496; EudraCT Number:2014-002988-16
Jules Gill-Peterson & Dr. Jerrica Kirkley: Who Gets to Transition in America? | Them Search Menu Story Saved Close Twitter Email Twitter Email Facebook Twitter Instagram
Trans historian Jules Gill-Peterson and Plume founder Dr. Jerrica Kirkley discuss the complex future of trans healthcare.
Murray's Mailbag: Two most impressive things about Nevada basketball's 2-0 start? | Nevada Sports Net
Discussing the Nevada men's basketball team's 2-0 start and plenty more (like Whitney Houston, spiked cocoa, Wolf Pack hockey and Hopper from Stranger Things).
Appeals court ruling keeps Biden student debt plan on hold - Alabama Daily News
The plan would cancel $10,000 in student loan debt for those making less than $125,000 or households with less than $250,000 in income. Pell Grant recipients, who typically demonstrate more financial need, would get an additional $10,000 in debt forgiven. The cancellation applies to federal student loans used to attend undergraduate and graduate school, along with Parent Plus loans. The Congressional Budget Office has said the program will cost about $400 billion over the next three decades.
Michigan Football will be hosting key 2023 targets for Illinois game
There has been a lot of positive buzz about Michigan football recruiting in the 2024 class, but what about 2023? Here are some visits to watch this weekend.
Thank You For Your Feedback VICE VICE
The community feedback process is an inconvenient annoyance that brings out the worst in people. It is also at the heart of why U.S. cities can't build new housing or transportation.
Google Pays $391 Million To Settle Location-Tracking Lawsuits
It’s the largest multi-state consumer privacy settlement ever.
College Football Week 11 Gut Reactions
Gut reactions throughout the day to all of the results from College Football Week 11.
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Power Outage FAQs
What is Power Outage?
Power outage (also called a power cut, a power blackout, power failure or a blackout) is a short-term or a long-term loss of the electric power to a particular area.
What Causes Power Outages?
- Severe weather (high winds, lightning, winter storms, heat waves, rain or flooding can cause damage to power lines or equipment);
- Other damage to electric transmission lines (vehicle accidents, trees, and animals can cause damage to power lines or equipment);
- Repairing, maintenance or upgrades on power lines and equipment.
What are the Top Outage Safety Tips?
- Stay away from the downed power lines, park vehicles in protected areas;
- Unplug appliances and electronics, limit cell phone use to conserve battery life;
- Use portable generators outdoors only, well away from open windows and doors;
- Pack perishable foods into a cooler, keep refrigerator and freezer doors shut as much as possible.
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Peterson, Alabama
| City | Peterson |
| County | Tuscaloosa |
| State | Alabama (AL) |
| Country | United States |
| Zip Codes | 35478 |